Weatherford, Okla. – A leaking tanker truck carrying 25,000 pounds of ammonia caused a toxic gas exposure outside a Holiday Inn Express in Weatherford, Oklahoma, Wednesday night, prompting the evacuation of hundreds of residents and sending 36 people to hospitals, local officials and the EPA reported.
The leak originated from a faulty gasket or valve on the tanker parked behind the hotel. An oil field worker staying at the hotel described hearing a “faint pop” before a strong ammonia odor filled the elevator and surrounding areas.
“His lips were purple and frozen shut. His eyes were bloodshot red. His skin was all red,” the witness recalled, describing his coworker’s critical condition before police intervened.
Medical Response
Emergency responders transported 36 patients to local hospitals, including 10 sent to facilities in Oklahoma City. As of early Thursday, four patients remained in critical condition.
Authorities emphasized the serious health risks of ammonia exposure, noting that the colorless, pungent gas can cause severe burns, respiratory distress, and life-threatening complications in high concentrations.
Community Evacuations and School Closures
The leak forced 500 to 600 residents to relocate to a temporary shelter, while others were ordered to remain indoors for several hours. Schools were closed, and local nursing homes were evacuated as a precaution.
Firefighters and hazmat teams, along with the Oklahoma National Guard, conducted door-to-door checks to ensure residents followed evacuation and shelter-in-place orders. The orders were lifted Thursday morning after the area was deemed safe.
Environmental Impact and Cleanup
The EPA monitored air, water, and soil conditions following the incident. Officials reported that ammonia levels in the surrounding residential areas were not detected, while pH levels in local creeks remained normal. Soil contamination was expected to neutralize naturally over a short period.
Clean-up efforts could take several days, and air quality will continue to be closely monitored. Authorities confirmed that the leak is no longer active.
Health Advisory
Exposure to ammonia can result in irritation of the eyes, skin, and respiratory system, and high concentrations may be fatal. Residents affected by the incident are urged to seek medical attention if symptoms such as burning, coughing, or difficulty breathing persist.
Do you live in the Weatherford area or have experience responding to chemical leaks? Share your insights in the comments below and join the conversation on community safety and emergency preparedness.

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